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cGMP-dependent protein kinase protects cGMP from hydrolysis by phosphodiesterase-5.

The physiological effects of cGMP are largely determined by the activities of intracellular receptors, including cGMP-dependent protein kinase (PKG) and cGMP-binding cyclic nucleotide phosphodiesterases (PDEs), and the distribution of cGMP among these receptors dictates activity of the signalling pa...

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Autores principales: Kotera, Jun, Grimes, Kennard A, Corbin, Jackie D, Francis, Sharron H
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223414/
https://ncbi.nlm.nih.gov/pubmed/12617722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030107
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