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Phosphodiesterases and Cardiac cGMP: Evolving Roles and Controversies
Cyclic guanosine monophosphate (cGMP) and its primary target kinase –protein kinase G (PKG) are well-recognized modulators of cardiac function and chronic stress response. Their enhancement appears to serve as a myocardial brake, reducing maladaptive hypertrophy, enhancing cell survival signaling an...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3106121/ https://ncbi.nlm.nih.gov/pubmed/21477871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2011.02.019 |
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