USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP

Human C-terminal binding protein (CtBP)–interacting protein (CtIP) is a central regulator to initiate DNA end resection and homologous recombination (HR). Several studies have shown that post-translational modifications control the activity or expression of CtIP. However, it remains unclear whether...

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Udgivet i:Nat Commun
Main Authors: Gao, Ming, Guo, Guijie, Huang, Jinzhou, Kloeber, Jake A., Zhao, Fei, Deng, Min, Tu, Xinyi, Kim, Wootae, Zhou, Qin, Zhang, Chao, Yin, Ping, Luo, Kuntian, Lou, Zhenkun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584643/
https://ncbi.nlm.nih.gov/pubmed/33097710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19202-0
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