Stromal platelet-derived growth factor receptor-β signaling promotes breast cancer metastasis in the brain

Platelet-derived growth factor receptor-beta (PDGFRβ) is a receptor tyrosine kinase found in cells of mesenchymal origin such as fibroblasts and pericytes. Activation of this receptor is dependent on paracrine ligand induction, and its preferred ligand PDGFB is released by neighboring epithelial and...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Thies, Katie A., Hammer, Anisha M., Hildreth, Blake E., Steck, Sarah A., Spehar, Jonathan M., Kladney, Raleigh D., Geisler, Jennifer A., Das, Manjusri, Russell, Luke O., Bey, Jerome F., Bolyard, Chelsea M., Pilarski, Robert, Trimboli, Anthony J., Cuitiño, Maria C., Koivisto, Christopher S., Stover, Daniel G., Schoenfield, Lynn, Otero, Jose, Godbout, Jonathan P., Chakravarti, Arnab, Ringel, Matthew D., Ramaswamy, Bhuvaneswari, Li, Zaibo, Kaur, Balveen, Leone, Gustavo, Ostrowski, Michael C., Sizemore, Steven T., Sizemore, Gina M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581545/
https://ncbi.nlm.nih.gov/pubmed/32327406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-3731
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