Synthesis, in vitro, and in vivo evaluation of novel N-phenylindazolyl diarylureas as potential anti-cancer agents

Novel N-phenylindazole based diarylureas have been designed, synthesized and evaluated as potential anticancer agents. In vitro cell viability studies of these derivatives illustrate good potency with IC(50) values in the range of 0.4–50 μM in several cancer cell lines including murine metastatic br...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Solano, Lucas N., Nelson, Grady L., Ronayne, Conor T., Jonnalagadda, Shirisha, Jonnalagadda, Sravan K., Kottke, Kaija, Chitren, Robert, Johnson, Joseph L., Pandey, Manoj K., Jonnalagadda, Subash C., Mereddy, Venkatram R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578069/
https://ncbi.nlm.nih.gov/pubmed/33087745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74572-1
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