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Monocarboxylate Transporter 1 Inhibitors as Potential Anticancer Agents
[Image: see text] Potent monocarboxylate transporter 1 inhibitors (MCT1) have been developed based on α-cyano-4-hydroxycinnamic acid template. Structure–activity relationship studies demonstrate that the introduction of p-N, N-dialkyl/diaryl, and o-methoxy groups into cyanocinnamic acid has maximal...
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| Udgivet i: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2015
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4434469/ https://ncbi.nlm.nih.gov/pubmed/26005533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00049 |
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