β-Amyloid Plaque Reduction in the Hippocampus After Focused Ultrasound-Induced Blood–Brain Barrier Opening in Alzheimer’s Disease

The blood–brain barrier (BBB) limits therapeutic delivery in Alzheimer’s disease (AD) and other neurological disorders. Animal models have demonstrated safe BBB opening and reduction in β-amyloid plaque with focused ultrasound (FUS). We recently demonstrated the feasibility, safety, and reversibilit...

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Veröffentlicht in:Front Hum Neurosci
Hauptverfasser: D’Haese, Pierre-François, Ranjan, Manish, Song, Alexander, Haut, Marc W., Carpenter, Jeffrey, Dieb, Gerard, Najib, Umer, Wang, Peng, Mehta, Rashi I., Chazen, J. Levi, Hodder, Sally, Claassen, Daniel, Kaplitt, Michael, Rezai, Ali R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575813/
https://ncbi.nlm.nih.gov/pubmed/33132889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnhum.2020.593672
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