Noninvasive hippocampal blood−brain barrier opening in Alzheimer’s disease with focused ultrasound

The blood–brain barrier (BBB) presents a significant challenge for treating brain disorders. The hippocampus is a key target for novel therapeutics, playing an important role in Alzheimer’s disease (AD), epilepsy, and depression. Preclinical studies have shown that magnetic resonance (MR)-guided low...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rezai, Ali R., Ranjan, Manish, D’Haese, Pierre-François, Haut, Marc W., Carpenter, Jeffrey, Najib, Umer, Mehta, Rashi I., Chazen, J. Levi, Zibly, Zion, Yates, Jennifer R., Hodder, Sally L., Kaplitt, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196825/
https://ncbi.nlm.nih.gov/pubmed/32284421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002571117
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