β-Amyloid Plaque Reduction in the Hippocampus After Focused Ultrasound-Induced Blood–Brain Barrier Opening in Alzheimer’s Disease

The blood–brain barrier (BBB) limits therapeutic delivery in Alzheimer’s disease (AD) and other neurological disorders. Animal models have demonstrated safe BBB opening and reduction in β-amyloid plaque with focused ultrasound (FUS). We recently demonstrated the feasibility, safety, and reversibilit...

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Detalhes bibliográficos
Publicado no:Front Hum Neurosci
Main Authors: D’Haese, Pierre-François, Ranjan, Manish, Song, Alexander, Haut, Marc W., Carpenter, Jeffrey, Dieb, Gerard, Najib, Umer, Wang, Peng, Mehta, Rashi I., Chazen, J. Levi, Hodder, Sally, Claassen, Daniel, Kaplitt, Michael, Rezai, Ali R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575813/
https://ncbi.nlm.nih.gov/pubmed/33132889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnhum.2020.593672
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