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A Study of Amyloid-β and Phosphotau in Plaques and Neurons in the Hippocampus of Alzheimer’s Disease Patients

The main pathological hallmarks in Alzheimer’s disease (AD) are the presence of extracellular amyloid plaques, primarily consisting of amyloid-β (Aβ) peptide, and the accumulation of paired helical filaments of hyperphosphorylated tau protein (PHF(-Tau)) within neurons. Since CA1 is one of the most...

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Dettagli Bibliografici
Pubblicato in:J Alzheimers Dis
Autori principali: Furcila, Diana, DeFelipe, Javier, Alonso-Nanclares, Lidia
Natura: Artigo
Lingua:Inglês
Pubblicazione: IOS Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027945/
https://ncbi.nlm.nih.gov/pubmed/29914033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180173
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