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A Study of Amyloid-β and Phosphotau in Plaques and Neurons in the Hippocampus of Alzheimer’s Disease Patients

The main pathological hallmarks in Alzheimer’s disease (AD) are the presence of extracellular amyloid plaques, primarily consisting of amyloid-β (Aβ) peptide, and the accumulation of paired helical filaments of hyperphosphorylated tau protein (PHF(-Tau)) within neurons. Since CA1 is one of the most...

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Vydáno v:J Alzheimers Dis
Hlavní autoři: Furcila, Diana, DeFelipe, Javier, Alonso-Nanclares, Lidia
Médium: Artigo
Jazyk:Inglês
Vydáno: IOS Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027945/
https://ncbi.nlm.nih.gov/pubmed/29914033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180173
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