Nanoscale structure of amyloid-β plaques in Alzheimer’s disease

Soluble amyloid-β (Aβ) is considered to be a critical component in the pathogenesis of Alzheimer’s disease (AD). Evidence suggests that these non-fibrillar Aβ assemblies are implicated in synaptic dysfunction, neurodegeneration and cell death. However, characterization of these species comes mainly...

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Udgivet i:Sci Rep
Main Authors: Querol-Vilaseca, Marta, Colom-Cadena, Martí, Pegueroles, Jordi, Nuñez-Llaves, Raúl, Luque-Cabecerans, Joan, Muñoz-Llahuna, Laia, Andilla, Jordi, Belbin, Olivia, Spires-Jones, Tara L., Gelpi, Ellen, Clarimon, Jordi, Loza-Alvarez, Pablo, Fortea, Juan, Lleó, Alberto
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435662/
https://ncbi.nlm.nih.gov/pubmed/30914681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41443-3
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