VAMP-2 is a surrogate cerebrospinal fluid marker of Alzheimer-related cognitive impairment in adults with Down syndrome

BACKGROUND: There is an urgent need for objective markers of Alzheimer’s disease (AD)-related cognitive impairment in people with Down syndrome (DS) to improve diagnosis, monitor disease progression, and assess response to disease-modifying therapies. Previously, GluA4 and neuronal pentraxin 2 (NPTX...

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Bibliografiske detaljer
Udgivet i:Alzheimers Res Ther
Main Authors: Lleó, Alberto, Carmona-Iragui, Maria, Videla, Laura, Fernández, Susana, Benejam, Bessy, Pegueroles, Jordi, Barroeta, Isabel, Altuna, Miren, Valldeneu, Silvia, Xiao, Mei-Fang, Xu, Desheng, Núñez-Llaves, Raúl, Querol-Vilaseca, Marta, Sirisi, Sònia, Bejanin, Alexandre, Iulita, M. Florencia, Clarimón, Jordi, Blesa, Rafael, Worley, Paul, Alcolea, Daniel, Fortea, Juan, Belbin, Olivia
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240298/
https://ncbi.nlm.nih.gov/pubmed/34183050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-021-00861-0
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