Cerebrospinal fluid profile of NPTX2 supports role of Alzheimer’s disease-related inhibitory circuit dysfunction in adults with Down syndrome

BACKGROUND: Alzheimer’s disease (AD) is the major cause of death in adults with Down syndrome (DS). There is an urgent need for objective markers of AD in the DS population to improve early diagnosis and monitor disease progression. NPTX2 has recently emerged as a promising cerebrospinal fluid (CSF)...

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Gepubliceerd in:Mol Neurodegener
Hoofdauteurs: Belbin, Olivia, Xiao, Mei-Fang, Xu, Desheng, Carmona-Iragui, Maria, Pegueroles, Jordi, Benejam, Bessy, Videla, Laura, Fernández, Susana, Barroeta, Isabel, Nuñez-Llaves, Raúl, Montal, Victor, Vilaplana, Eduard, Altuna, Miren, Clarimón, Jordi, Alcolea, Daniel, Blesa, Rafael, Lleó, Alberto, Worley, Paul F., Fortea, Juan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433053/
https://ncbi.nlm.nih.gov/pubmed/32807227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00398-0
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