Synaptic phosphorylated α-synuclein in dementia with Lewy bodies

Dementia with Lewy bodies is characterized by the accumulation of Lewy bodies and Lewy neurites in the CNS, both of which are composed mainly of aggregated α-synuclein phosphorylated at Ser129. Although phosphorylated α-synuclein is believed to exert toxic effects at the synapse in dementia with Lew...

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Publicado en:Brain
Autores principales: Colom-Cadena, Martí, Pegueroles, Jordi, Herrmann, Abigail G, Henstridge, Christopher M, Muñoz, Laia, Querol-Vilaseca, Marta, Martín-Paniello, Carla San, Luque-Cabecerans, Joan, Clarimon, Jordi, Belbin, Olivia, Núñez-Llaves, Raúl, Blesa, Rafael, Smith, Colin, McKenzie, Chris-Anne, Frosch, Matthew P, Roe, Allyson, Fortea, Juan, Andilla, Jordi, Loza-Alvarez, Pablo, Gelpi, Ellen, Hyman, Bradley T, Spires-Jones, Tara L, Lleó, Alberto
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841145/
https://ncbi.nlm.nih.gov/pubmed/29177427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awx275
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