Synaptic phosphorylated α-synuclein in dementia with Lewy bodies

Dementia with Lewy bodies is characterized by the accumulation of Lewy bodies and Lewy neurites in the CNS, both of which are composed mainly of aggregated α-synuclein phosphorylated at Ser129. Although phosphorylated α-synuclein is believed to exert toxic effects at the synapse in dementia with Lew...

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Vydáno v:Brain
Hlavní autoři: Colom-Cadena, Martí, Pegueroles, Jordi, Herrmann, Abigail G, Henstridge, Christopher M, Muñoz, Laia, Querol-Vilaseca, Marta, Martín-Paniello, Carla San, Luque-Cabecerans, Joan, Clarimon, Jordi, Belbin, Olivia, Núñez-Llaves, Raúl, Blesa, Rafael, Smith, Colin, McKenzie, Chris-Anne, Frosch, Matthew P, Roe, Allyson, Fortea, Juan, Andilla, Jordi, Loza-Alvarez, Pablo, Gelpi, Ellen, Hyman, Bradley T, Spires-Jones, Tara L, Lleó, Alberto
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841145/
https://ncbi.nlm.nih.gov/pubmed/29177427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awx275
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