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Synaptic phosphorylated α-synuclein in dementia with Lewy bodies

Dementia with Lewy bodies is characterized by the accumulation of Lewy bodies and Lewy neurites in the CNS, both of which are composed mainly of aggregated α-synuclein phosphorylated at Ser129. Although phosphorylated α-synuclein is believed to exert toxic effects at the synapse in dementia with Lew...

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Detalhes bibliográficos
Publicado no:Brain
Principais autores: Colom-Cadena, Martí, Pegueroles, Jordi, Herrmann, Abigail G, Henstridge, Christopher M, Muñoz, Laia, Querol-Vilaseca, Marta, Martín-Paniello, Carla San, Luque-Cabecerans, Joan, Clarimon, Jordi, Belbin, Olivia, Núñez-Llaves, Raúl, Blesa, Rafael, Smith, Colin, McKenzie, Chris-Anne, Frosch, Matthew P, Roe, Allyson, Fortea, Juan, Andilla, Jordi, Loza-Alvarez, Pablo, Gelpi, Ellen, Hyman, Bradley T, Spires-Jones, Tara L, Lleó, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841145/
https://ncbi.nlm.nih.gov/pubmed/29177427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awx275
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