β-Amyloid Plaque Reduction in the Hippocampus After Focused Ultrasound-Induced Blood–Brain Barrier Opening in Alzheimer’s Disease

The blood–brain barrier (BBB) limits therapeutic delivery in Alzheimer’s disease (AD) and other neurological disorders. Animal models have demonstrated safe BBB opening and reduction in β-amyloid plaque with focused ultrasound (FUS). We recently demonstrated the feasibility, safety, and reversibilit...

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Dettagli Bibliografici
Pubblicato in:Front Hum Neurosci
Autori principali: D’Haese, Pierre-François, Ranjan, Manish, Song, Alexander, Haut, Marc W., Carpenter, Jeffrey, Dieb, Gerard, Najib, Umer, Wang, Peng, Mehta, Rashi I., Chazen, J. Levi, Hodder, Sally, Claassen, Daniel, Kaplitt, Michael, Rezai, Ali R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575813/
https://ncbi.nlm.nih.gov/pubmed/33132889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnhum.2020.593672
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