β-Amyloid Plaque Reduction in the Hippocampus After Focused Ultrasound-Induced Blood–Brain Barrier Opening in Alzheimer’s Disease

The blood–brain barrier (BBB) limits therapeutic delivery in Alzheimer’s disease (AD) and other neurological disorders. Animal models have demonstrated safe BBB opening and reduction in β-amyloid plaque with focused ultrasound (FUS). We recently demonstrated the feasibility, safety, and reversibilit...

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Bibliografiske detaljer
Udgivet i:Front Hum Neurosci
Main Authors: D’Haese, Pierre-François, Ranjan, Manish, Song, Alexander, Haut, Marc W., Carpenter, Jeffrey, Dieb, Gerard, Najib, Umer, Wang, Peng, Mehta, Rashi I., Chazen, J. Levi, Hodder, Sally, Claassen, Daniel, Kaplitt, Michael, Rezai, Ali R.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575813/
https://ncbi.nlm.nih.gov/pubmed/33132889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnhum.2020.593672
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