β-Amyloid Plaque Reduction in the Hippocampus After Focused Ultrasound-Induced Blood–Brain Barrier Opening in Alzheimer’s Disease

The blood–brain barrier (BBB) limits therapeutic delivery in Alzheimer’s disease (AD) and other neurological disorders. Animal models have demonstrated safe BBB opening and reduction in β-amyloid plaque with focused ultrasound (FUS). We recently demonstrated the feasibility, safety, and reversibilit...

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Dades bibliogràfiques
Publicat a:Front Hum Neurosci
Autors principals: D’Haese, Pierre-François, Ranjan, Manish, Song, Alexander, Haut, Marc W., Carpenter, Jeffrey, Dieb, Gerard, Najib, Umer, Wang, Peng, Mehta, Rashi I., Chazen, J. Levi, Hodder, Sally, Claassen, Daniel, Kaplitt, Michael, Rezai, Ali R.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575813/
https://ncbi.nlm.nih.gov/pubmed/33132889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnhum.2020.593672
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