Caricamento...
Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex
The human cis-prenyltransferase (hcis-PT) is an enzymatic complex essential for protein N-glycosylation. Synthesizing the precursor of the glycosyl carrier dolichol-phosphate, mutations in hcis-PT cause severe human diseases. Here, we reveal that hcis-PT exhibits a heterotetrameric assembly in solut...
Salvato in:
| Pubblicato in: | Nat Commun |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7573591/ https://ncbi.nlm.nih.gov/pubmed/33077723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18970-z |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|