Structural Characterization of Full-Length Human Dehydrodolichyl Diphosphate Synthase Using an Integrative Computational and Experimental Approach

Dehydrodolichyl diphosphate synthase (DHDDS) is the catalytic subunit of the heteromeric human cis-prenyltransferase complex, synthesizing the glycosyl carrier precursor for N-linked protein glycosylation. Consistent with the important role of N-glycosylation in protein biogenesis, DHDDS mutations r...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Lisnyansky Bar-El, Michal, Lee, Su Youn, Ki, Ah Young, Kapelushnik, Noa, Loewenstein, Anat, Chung, Ka Young, Schneidman-Duhovny, Dina, Giladi, Moshe, Newman, Hadas, Haitin, Yoni
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921004/
https://ncbi.nlm.nih.gov/pubmed/31661879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110660
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