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Structure of KCNH2 cyclic nucleotide-binding homology domain reveals a functionally vital salt-bridge
Human KCNH2 channels (hKCNH2, ether-à-go-go [EAG]–related gene, hERG) are best known for their contribution to cardiac action potential repolarization and have key roles in various pathologies. Like other KCNH family members, hKCNH2 channels contain a unique intracellular complex, consisting of an N...
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| Veröffentlicht in: | J Gen Physiol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7141593/ https://ncbi.nlm.nih.gov/pubmed/32191791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201912505 |
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