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Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity

Cyclic AMP and cyclic GMP are ubiquitous second messengers that regulate the activity of effector proteins in all forms of life. The main effector proteins, the 3′,5′-cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) and the 3′,5′-cyclic guanosine monophosphate (cGMP)-dependent pr...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Lorenz, Robin, Moon, Eui-Whan, Kim, Jeong Joo, Schmidt, Sven H., Sankaran, Banumathi, Pavlidis, Ioannis V., Kim, Choel, Herberg, Friedrich W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896744/
https://ncbi.nlm.nih.gov/pubmed/28583991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160969
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