Pan-enteric neuropathy and dysmotility are present in a mouse model of short-segment Hirschsprung disease and may contribute to post-pullthrough morbidity

PURPOSE: Hirschsprung disease (HSCR) is characterized by distal intestinal aganglionosis. While surgery is lifesaving, gastrointestinal (GI) motility disorders persist in many patients. Our objective was to determine whether enteric nervous system (ENS) abnormalities exist in the ganglionated portio...

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Veröffentlicht in:J Pediatr Surg
Hauptverfasser: Bhave, Sukhada, Arciero, Emily, Baker, Corey, Ho, Wing Lam, Guyer, Richard A., Hotta, Ryo, Goldstein, Allan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572464/
https://ncbi.nlm.nih.gov/pubmed/32414519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2020.04.002
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