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Enteric neuronal cell therapy reverses architectural changes in a novel diphtheria toxin-mediated model of colonic aganglionosis

Hirschsprung disease (HSCR) is characterized by absence of the enteric nervous system (ENS) in the distal bowel. Despite removal of the aganglionic segment, gastrointestinal (GI) problems persist. Cell therapy offers potential treatment but use of genetic models is limited by their poor survival. We...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Bhave, Sukhada, Arciero, Emily, Baker, Corey, Ho, Wing Lam, Stavely, Rhian, Goldstein, Allan M., Hotta, Ryo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904570/
https://ncbi.nlm.nih.gov/pubmed/31822721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55128-4
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