Pan-enteric neuropathy and dysmotility are present in a mouse model of short-segment Hirschsprung disease and may contribute to post-pullthrough morbidity

PURPOSE: Hirschsprung disease (HSCR) is characterized by distal intestinal aganglionosis. While surgery is lifesaving, gastrointestinal (GI) motility disorders persist in many patients. Our objective was to determine whether enteric nervous system (ENS) abnormalities exist in the ganglionated portio...

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發表在:J Pediatr Surg
Main Authors: Bhave, Sukhada, Arciero, Emily, Baker, Corey, Ho, Wing Lam, Guyer, Richard A., Hotta, Ryo, Goldstein, Allan M.
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572464/
https://ncbi.nlm.nih.gov/pubmed/32414519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2020.04.002
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