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Bowel dysfunction following pullthrough surgery is associated with an overabundance of nitrergic neurons in Hirschsprung disease

PURPOSE: Recent evidence suggests that patients with Hirschsprung disease (HD) have abnormal neurotransmitter expression in the ganglionated proximal colon. These alterations may cause persistent bowel dysfunction even after pullthrough surgery. We sought to quantify the proportion of nitrergic neur...

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Publicat a:J Pediatr Surg
Autors principals: Cheng, Lily S., Schwartz, Dana M., Hotta, Ryo, Graham, Hannah K., Goldstein, Allan M.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065396/
https://ncbi.nlm.nih.gov/pubmed/27570241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2016.08.001
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