Nuclear receptor REVERBα is a state-dependent regulator of liver energy metabolism

The nuclear receptor REVERBα is a core component of the circadian clock and proposed to be a dominant regulator of hepatic lipid metabolism. Using antibody-independent ChIP-sequencing of REVERBα in mouse liver, we reveal a high-confidence cistrome and define direct target genes. REVERBα-binding site...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Hunter, A. Louise, Pelekanou, Charlotte E., Adamson, Antony, Downton, Polly, Barron, Nichola J., Cornfield, Thomas, Poolman, Toryn M., Humphreys, Neil, Cunningham, Peter S., Hodson, Leanne, Loudon, Andrew S. I., Iqbal, Mudassar, Bechtold, David A., Ray, David W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568238/
https://ncbi.nlm.nih.gov/pubmed/32989157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005330117
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi