Remote loading paclitaxel–doxorubicin prodrug into liposomes for cancer combination therapy

The combination of paclitaxel (PTX) and doxorubicin (DOX) has been widely used in the clinic. However, it remains unsatisfied due to the generation of severe toxicity. Previously, we have successfully synthesized a prodrug PTX-S-DOX (PSD). The prodrug displayed comparable in vitro cytotoxicity compa...

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Vydáno v:Acta Pharm Sin B
Hlavní autoři: Yu, Jiang, Wang, Yingli, Zhou, Shuang, Li, Jinbo, Wang, Jiamei, Chi, Dongxu, Wang, Xue, Lin, Guimei, He, Zhonggui, Wang, Yongjun
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564015/
https://ncbi.nlm.nih.gov/pubmed/33088692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2020.04.011
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