Remote loading paclitaxel–doxorubicin prodrug into liposomes for cancer combination therapy

The combination of paclitaxel (PTX) and doxorubicin (DOX) has been widely used in the clinic. However, it remains unsatisfied due to the generation of severe toxicity. Previously, we have successfully synthesized a prodrug PTX-S-DOX (PSD). The prodrug displayed comparable in vitro cytotoxicity compa...

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Dettagli Bibliografici
Pubblicato in:Acta Pharm Sin B
Autori principali: Yu, Jiang, Wang, Yingli, Zhou, Shuang, Li, Jinbo, Wang, Jiamei, Chi, Dongxu, Wang, Xue, Lin, Guimei, He, Zhonggui, Wang, Yongjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564015/
https://ncbi.nlm.nih.gov/pubmed/33088692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2020.04.011
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