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Remote loading paclitaxel–doxorubicin prodrug into liposomes for cancer combination therapy

The combination of paclitaxel (PTX) and doxorubicin (DOX) has been widely used in the clinic. However, it remains unsatisfied due to the generation of severe toxicity. Previously, we have successfully synthesized a prodrug PTX-S-DOX (PSD). The prodrug displayed comparable in vitro cytotoxicity compa...

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Bibliografische gegevens
Gepubliceerd in:Acta Pharm Sin B
Hoofdauteurs: Yu, Jiang, Wang, Yingli, Zhou, Shuang, Li, Jinbo, Wang, Jiamei, Chi, Dongxu, Wang, Xue, Lin, Guimei, He, Zhonggui, Wang, Yongjun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564015/
https://ncbi.nlm.nih.gov/pubmed/33088692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2020.04.011
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