Remote loading paclitaxel–doxorubicin prodrug into liposomes for cancer combination therapy

The combination of paclitaxel (PTX) and doxorubicin (DOX) has been widely used in the clinic. However, it remains unsatisfied due to the generation of severe toxicity. Previously, we have successfully synthesized a prodrug PTX-S-DOX (PSD). The prodrug displayed comparable in vitro cytotoxicity compa...

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Detalles Bibliográficos
Publicado en:Acta Pharm Sin B
Main Authors: Yu, Jiang, Wang, Yingli, Zhou, Shuang, Li, Jinbo, Wang, Jiamei, Chi, Dongxu, Wang, Xue, Lin, Guimei, He, Zhonggui, Wang, Yongjun
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2020
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564015/
https://ncbi.nlm.nih.gov/pubmed/33088692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2020.04.011
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