Remote loading paclitaxel–doxorubicin prodrug into liposomes for cancer combination therapy

The combination of paclitaxel (PTX) and doxorubicin (DOX) has been widely used in the clinic. However, it remains unsatisfied due to the generation of severe toxicity. Previously, we have successfully synthesized a prodrug PTX-S-DOX (PSD). The prodrug displayed comparable in vitro cytotoxicity compa...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Yu, Jiang, Wang, Yingli, Zhou, Shuang, Li, Jinbo, Wang, Jiamei, Chi, Dongxu, Wang, Xue, Lin, Guimei, He, Zhonggui, Wang, Yongjun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564015/
https://ncbi.nlm.nih.gov/pubmed/33088692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2020.04.011
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