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Iron-doxorubicin prodrug loaded liposome nanogenerator programs multimodal ferroptosis for efficient cancer therapy

Ferroptosis is a new mode of cell death, which can be induced by Fenton reaction-mediated lipid peroxidation. However, the insufficient H2O2 and high GSH in tumor cells restrict the efficiency of Fenton reaction-dependent ferroptosis. Herein, a self-supplying lipid peroxide nanoreactor was developed...

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Bibliografiske detaljer
Principais autores: Yinxian Yang, Shiyi Zuo, Linxiao Li, Xiao Kuang, Jinbo Li, Bingjun Sun, Shujun Wang, Zhonggui He, Jin Sun
Format: Artigo
Sprog:Inglês
Udgivet: KeAi Communications Co., Ltd. 2021-11-01
Serier:Asian Journal of Pharmaceutical Sciences
Fag:
Online adgang:http://www.sciencedirect.com/science/article/pii/S1818087621000404
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