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Is There Evidence for IGF1R-Stimulating Abs in Graves’ Orbitopathy Pathogenesis?
In this review, we summarize the evidence against direct stimulation of insulin-like growth factor 1 receptors (IGF1Rs) by autoantibodies in Graves’ orbitopathy (GO) pathogenesis. We describe a model of thyroid-stimulating hormone (TSH) receptor (TSHR)/IGF1R crosstalk and present evidence that obser...
Shranjeno v:
izdano v: | Int J Mol Sci |
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Main Authors: | , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
MDPI
2020
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7555308/ https://ncbi.nlm.nih.gov/pubmed/32911689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186561 |
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