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Role of IGF-1 pathway in the pathogenesis of Graves’ orbitopathy

The etiology of Graves’ orbitopathy (GO) remains enigmatic and thus controversy surrounds its pathogenesis. The role of the TSH receptor (TSHR) and the activating antibodies directed against it in the hyperthyroidism of Graves’ disease (GD) is firmly established. Less well elucidated is what part th...

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Detalhes bibliográficos
Main Authors: Smith, Terry J., Huetwell, Frederick G.L., Hegedüs, Laszlo, Douglas, Raymond S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712747/
https://ncbi.nlm.nih.gov/pubmed/22632366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beem.2011.10.002
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