The Pathophysiology of Thyroid Eye Disease (TED): Implications for Immunotherapy

Por Gupta, Shivani, Douglas, Raymond
Publicado em 2011

PGE(2) Induces IL-6 in Orbital Fibroblasts through EP2 Receptors and Increased Gene Promoter Activity: Implications to Thyroid-Associated Ophthalmopathy

Por Raychaudhuri, Nupur, Douglas, Raymond S., Smith, Terry J.
Publicado em 2010

Advances in the Management of Thyroid Eye Disease

Por Briceño, César A., Gupta, Shivani, Douglas, Raymond S.
Publicado em 2013

Thyroid-associated orbitopathy: Current insights into the pathophysiology, immunology and management

Por Bhatt, Rina, Nelson, Christine C., Douglas, Raymond S.
Publicado em 2010

Thyroid Eye Disease: Towards an Evidence Base for Treatment in the 21st Century

Por Gillespie, Erin F., Smith, Terry J., Douglas, Raymond S.
Publicado em 2012

Thyrotropin Receptor and CD40 Mediate Interleukin-8 Expression in Fibrocytes: Implications for Thyroid-Associated Ophthalmopathy (An American Ophthalmological Society Thesis)

Por Douglas, Raymond S., Mester, Tünde, Ginter, Anna, Kim, Denise S.
Publicado no Trans Am Ophthalmol Soc (2014)

Targeted biological therapies for Graves’ disease and thyroid associated ophthalmopathy. Focus on B cell depletion with Rituximab

Por Hegedüs, Laszlo, Smith, Terry J., Douglas, Raymond S., Nielsen, Ciaus H.
Publicado em 2011

Role of IGF-1 pathway in the pathogenesis of Graves’ orbitopathy

Por Smith, Terry J., Huetwell, Frederick G.L., Hegedüs, Laszlo, Douglas, Raymond S.
Publicado em 2012

Divergent Frequencies of IGF-I Receptor-Expressing Blood Lymphocytes in Monozygotic Twin Pairs Discordant for Graves’ Disease: Evidence for a Phenotypic Signature Ascribable to Non...

Por Douglas, Raymond S., Brix, Thomas H., Hwang, Catherine J., Hegedüs, Laszlo, Smith, Terry J.
Publicado em 2009

TSH-Mediated TNFα Production in Human Fibrocytes Is Inhibited by Teprotumumab, an IGF-1R Antagonist

Por Chen, Hong, Shan, Shannon J. C., Mester, Tünde, Wei, Yi-Hsuan, Douglas, Raymond S.
Publicado no PLoS One (2015)

Thyrotropin and CD40L Stimulate Interleukin-12 Expression in Fibrocytes: Implications for Pathogenesis of Thyroid-Associated Ophthalmopathy

Por Wu, Tong, Mester, Tünde, Gupta, Shivani, Sun, Fengyuan, Smith, Terry J., Douglas, Raymond S.
Publicado no Thyroid (2016)

Immunopathogenesis of Thyroid Eye Disease: Emerging Paradigms

Por Naik, Vibhavari M, Naik, Milind N, Goldberg, Robert A, Smith, Terry J, Douglas, Raymond S
Publicado em 2010

CD40 Expression in Fibrocytes Is Induced by TSH: Potential Synergistic Immune Activation

Por Mester, Tünde, Raychaudhuri, Nupur, Gillespie, Erin F., Chen, Hong, Smith, Terry J., Douglas, Raymond S.
Publicado no PLoS One (2016)

Orbital fibrosis in a mouse model of Graves' disease induced by genetic immunization of thyrotropin receptor cDNA

Por Zhao, Shuang-Xia, Tsui, Shanli, Cheung, Anthony, Douglas, Raymond S, Smith, Terry J, Banga, J Paul
Publicado em 2011

Human fibrocytes coexpress thyroglobulin and thyrotropin receptor

Por Fernando, Roshini, Atkins, Stephen, Raychaudhuri, Nupur, Lu, Ying, Li, Bin, Douglas, Raymond S., Smith, Terry J.
Publicado em 2012

Increased CD40(+) fibrocytes in patients with idiopathic orbital inflammation

Por Lee, Brian J, Atkins, Stephen, Ginter, Anna, Elner, Victor M, Nelson, Christine C, Douglas, Raymond S
Publicado no Ophthal Plast Reconstr Surg (2015)

Teprotumumab, an IGF-1R Blocking Monoclonal Antibody Inhibits TSH and IGF-1 Action in Fibrocytes

Por Chen, Hong, Mester, Tünde, Raychaudhuri, Nupur, Kauh, Courtney Y., Gupta, Shivani, Smith, Terry J., Douglas, Raymond S.
Publicado em 2014

Nuclear Targeting of IGF-1 Receptor in Orbital Fibroblasts from Graves' Disease: Apparent Role of ADAM17

Por Hoa, Neil, Tsui, Shanli, Afifiyan, Nikoo F., Sinha Hikim, Amiya, Li, Bin, Douglas, Raymond S., Smith, Terry J.
Publicado em 2012

Rituximab (Rituxan) Therapy for Severe Thyroid-Associated Ophthalmopathy Diminishes IGF-1R(+) T Cells

Por McCoy, Allison N., Kim, Denise S., Gillespie, Erin F., Atkins, Stephen J., Smith, Terry J., Douglas, Raymond S.
Publicado no J Clin Endocrinol Metab (2014)

Compressive Optic Neuropathy and Repeat Orbital Decompression: A Case Series

Por Kauh, Courtney Y., Gupta, Shivani, Douglas, Raymond S., Elner, Victor M., Nelson, Christine C., Niziol, Leslie M., Kahana, Alon
Publicado no Ophthal Plast Reconstr Surg (2015)