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Rituximab (Rituxan) Therapy for Severe Thyroid-Associated Ophthalmopathy Diminishes IGF-1R(+) T Cells

CONTEXT: Rituximab depletes CD20(+) B cells and has shown potential benefit in thyroid-associated ophthalmopathy (TAO). The impact of rituximab on T cell phenotype in TAO is unexplored. OBJECTIVE: The objective of the study was to quantify the abundance of IGF-I receptor-positive (IGF-1R(+)) CD4 and...

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Bibliografiske detaljer
Udgivet i:J Clin Endocrinol Metab
Main Authors: McCoy, Allison N., Kim, Denise S., Gillespie, Erin F., Atkins, Stephen J., Smith, Terry J., Douglas, Raymond S.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399483/
https://ncbi.nlm.nih.gov/pubmed/24670080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-3207
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