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Orbital fibrosis in a mouse model of Graves' disease induced by genetic immunization of thyrotropin receptor cDNA

The TSH receptor (TSHR) is the critical target for antibody production in Graves' disease (GD). Insulin-like growth factor 1 receptor (IGF1R) has been proposed as a second autoantigen in complications of GD such as orbitopathy. We attempted to induce orbital tissue remodeling in mice undergoing...

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Detalhes bibliográficos
Main Authors: Zhao, Shuang-Xia, Tsui, Shanli, Cheung, Anthony, Douglas, Raymond S, Smith, Terry J, Banga, J Paul
Formato: Artigo
Idioma:Inglês
Publicado em: BioScientifica 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152291/
https://ncbi.nlm.nih.gov/pubmed/21715431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-11-0162
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