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Divergent Sp1 Protein Levels May Underlie Differential Expression of UDP-Glucose Dehydrogenase by Fibroblasts: ROLE IN SUSCEPTIBILITY TO ORBITAL GRAVES DISEASE

UDP-glucose dehydrogenase (UGDH) catalyzes the formation of UDP-glucuronate. Glucuronate represents an integral component of the glycosaminoglycan, hyaluronan, which accumulates in orbital Graves disease. Here we report that orbital fibroblasts express higher levels of UGDH than do those from skin....

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Detalhes bibliográficos
Main Authors: Tsui, Shanli, Fernando, Roshini, Chen, Beiling, Smith, Terry J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129228/
https://ncbi.nlm.nih.gov/pubmed/21576248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.241166
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