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Divergent Sp1 Protein Levels May Underlie Differential Expression of UDP-Glucose Dehydrogenase by Fibroblasts: ROLE IN SUSCEPTIBILITY TO ORBITAL GRAVES DISEASE

UDP-glucose dehydrogenase (UGDH) catalyzes the formation of UDP-glucuronate. Glucuronate represents an integral component of the glycosaminoglycan, hyaluronan, which accumulates in orbital Graves disease. Here we report that orbital fibroblasts express higher levels of UGDH than do those from skin....

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Autori principali: Tsui, Shanli, Fernando, Roshini, Chen, Beiling, Smith, Terry J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129228/
https://ncbi.nlm.nih.gov/pubmed/21576248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.241166
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