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Slit2 may underlie divergent induction by thyrotropin of IL-23 and IL-12 in human fibrocytes

IL-23 and IL-12, two structurally related heterodimeric cytokines sharing a common subunit, divergently promote T helper cell development and expansion. Both cytokines have been implicated in the pathogenesis of thyroid-associated ophthalmopathy (TAO), an autoimmune component of Graves’ disease. In...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Fernando, Roshini, Atkins, Stephen J., Smith, Terry J.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7365299/
https://ncbi.nlm.nih.gov/pubmed/32086386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900434
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