TSH/IGF-1 Receptor Cross Talk in Graves' Ophthalmopathy Pathogenesis

CONTEXT: The TSH receptor (TSHR) is considered the main target of stimulatory autoantibodies in the pathogenesis of Graves' ophthalmopathy (GO); however, it has been suggested that stimulatory IGF-1 receptor (IGF-1R) autoantibodies also play a role. OBJECTIVE: We previously demonstrated that a...

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Pubblicato in:J Clin Endocrinol Metab
Autori principali: Krieger, Christine C., Place, Robert F., Bevilacqua, Carmine, Marcus-Samuels, Bernice, Abel, Brent S., Skarulis, Monica C., Kahaly, George J., Neumann, Susanne, Gershengorn, Marvin C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2016
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891793/
https://ncbi.nlm.nih.gov/pubmed/27043163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-1315
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