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Bidirectional TSH and IGF-1 Receptor Cross Talk Mediates Stimulation of Hyaluronan Secretion by Graves' Disease Immunoglobins

CONTEXT: There is no pathogenetically linked medical therapy for Graves' ophthalmopathy (GO). Lack of animal models and conflicting in vitro studies have hindered the development of such therapy. Recent reports propose that Graves' Igs bind to and activate thyrotropin receptors (TSHRs) and...

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Detalles Bibliográficos
Publicado en:J Clin Endocrinol Metab
Main Authors: Krieger, Christine C., Neumann, Susanne, Place, Robert F., Marcus-Samuels, Bernice, Gershengorn, Marvin C.
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333041/
https://ncbi.nlm.nih.gov/pubmed/25485727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-3566
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