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Bidirectional TSH and IGF-1 Receptor Cross Talk Mediates Stimulation of Hyaluronan Secretion by Graves' Disease Immunoglobins

CONTEXT: There is no pathogenetically linked medical therapy for Graves' ophthalmopathy (GO). Lack of animal models and conflicting in vitro studies have hindered the development of such therapy. Recent reports propose that Graves' Igs bind to and activate thyrotropin receptors (TSHRs) and...

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Dades bibliogràfiques
Publicat a:J Clin Endocrinol Metab
Autors principals: Krieger, Christine C., Neumann, Susanne, Place, Robert F., Marcus-Samuels, Bernice, Gershengorn, Marvin C.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333041/
https://ncbi.nlm.nih.gov/pubmed/25485727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-3566
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