Evidence That Graves' Ophthalmopathy Immunoglobulins Do Not Directly Activate IGF-1 Receptors

Background: Graves' ophthalmopathy (GO) pathogenesis involves thyrotropin (TSH) receptor (TSHR)-stimulating autoantibodies. Whether there are autoantibodies that directly stimulate insulin-like growth factor 1 receptors (IGF-1Rs), stimulating insulin-like growth factor receptor antibodies (IGFR...

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Detalles Bibliográficos
Publicado en:Thyroid
Main Authors: Marcus-Samuels, Bernice, Krieger, Christine C., Boutin, Alisa, Kahaly, George J., Neumann, Susanne, Gershengorn, Marvin C.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2018
Assuntos:
Immunology, Autoimmunity, and Graves' Ophthalmopathy
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952334/
https://ncbi.nlm.nih.gov/pubmed/29631510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2018.0089
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