लोड हो रहा है...
Dietary thiamine influences l-asparaginase sensitivity in a subset of leukemia cells
Tumor environment influences anticancer therapy response but which extracellular nutrients affect drug sensitivity is largely unknown. Using functional genomics, we determine modifiers of l-asparaginase (ASNase) response and identify thiamine pyrophosphate kinase 1 as a metabolic dependency under AS...
में बचाया:
| में प्रकाशित: | Sci Adv |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Association for the Advancement of Science
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7546708/ https://ncbi.nlm.nih.gov/pubmed/33036978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc7120 |
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