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Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumors
As oxygen is essential for many metabolic pathways, tumor hypoxia may impair cancer cell proliferation (1–4). However, the limiting metabolites for proliferation under hypoxia and in tumors are unknown. Here, we assessed proliferation of a collection of cancer cells upon inhibition of the mitochondr...
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| 發表在: | Nat Cell Biol |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6030478/ https://ncbi.nlm.nih.gov/pubmed/29941933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0118-z |
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