CHP1 regulates compartmentalized glycerolipid synthesis by activating GPAT4

Cells require a constant supply of fatty acids to survive and proliferate. Fatty acids incorporate into membrane and storage glycerolipids through a series of endoplasmic reticulum (ER) enzymes, but how these enzymes are regulated is not well understood. Here, using a combination of CRISPR-based gen...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Mol Cell
Hlavní autoři: Zhu, Xiphias Ge, Puthenveedu, Shirony Nicholson, Shen, Yihui, La, Konnor, Ozlu, Can, Wang, Tim, Klompstra, Diana, Gultekin, Yetis, Chi, Jingyi, Fidelin, Justine, Peng, Tao, Molina, Henrik, Hang, Howard C., Min, Wei, Birsoy, Kıvanç
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450717/
https://ncbi.nlm.nih.gov/pubmed/30846317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.01.037
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky