CHP1 regulates compartmentalized glycerolipid synthesis by activating GPAT4

Cells require a constant supply of fatty acids to survive and proliferate. Fatty acids incorporate into membrane and storage glycerolipids through a series of endoplasmic reticulum (ER) enzymes, but how these enzymes are regulated is not well understood. Here, using a combination of CRISPR-based gen...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell
Egile Nagusiak: Zhu, Xiphias Ge, Puthenveedu, Shirony Nicholson, Shen, Yihui, La, Konnor, Ozlu, Can, Wang, Tim, Klompstra, Diana, Gultekin, Yetis, Chi, Jingyi, Fidelin, Justine, Peng, Tao, Molina, Henrik, Hang, Howard C., Min, Wei, Birsoy, Kıvanç
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450717/
https://ncbi.nlm.nih.gov/pubmed/30846317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.01.037
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