miR-125a-5p regulates megakaryocyte proplatelet formation via the actin-bundling protein L-plastin

There is heritability to interindividual variation in platelet count, and better understanding of the regulating genetic factors may provide insights for thrombopoiesis. MicroRNAs (miRs) regulate gene expression in health and disease, and megakaryocytes (MKs) deficient in miRs have lower platelet co...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Bhatlekar, Seema, Manne, Bhanu K., Basak, Indranil, Edelstein, Leonard C., Tugolukova, Emilia, Stoller, Michelle L., Cody, Mark J., Morley, Sharon C., Nagalla, Srikanth, Weyrich, Andrew S., Rowley, Jesse W., O’Connell, Ryan M., Rondina, Matthew T., Campbell, Robert A., Bray, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544541/
https://ncbi.nlm.nih.gov/pubmed/32844999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005230
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