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miR-125a-5p regulates megakaryocyte proplatelet formation via the actin-bundling protein L-plastin

There is heritability to interindividual variation in platelet count, and better understanding of the regulating genetic factors may provide insights for thrombopoiesis. MicroRNAs (miRs) regulate gene expression in health and disease, and megakaryocytes (MKs) deficient in miRs have lower platelet co...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Bhatlekar, Seema, Manne, Bhanu K., Basak, Indranil, Edelstein, Leonard C., Tugolukova, Emilia, Stoller, Michelle L., Cody, Mark J., Morley, Sharon C., Nagalla, Srikanth, Weyrich, Andrew S., Rowley, Jesse W., O’Connell, Ryan M., Rondina, Matthew T., Campbell, Robert A., Bray, Paul F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544541/
https://ncbi.nlm.nih.gov/pubmed/32844999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005230
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