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The NLRP3–inflammasome as a sensor of organelle dysfunction

Diverse pathogen- and damage-associated stresses drive inflammation via activation of the multimolecular NLRP3–inflammasome complex. How the effects of diverse stimuli are integrated by the cell to regulate NLRP3 has been the subject of intense research, and yet an accepted unifying hypothesis for t...

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Bibliografische gegevens
Gepubliceerd in:J Cell Biol
Hoofdauteurs: Seoane, Paula I., Lee, Bali, Hoyle, Christopher, Yu, Shi, Lopez-Castejon, Gloria, Lowe, Martin, Brough, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Rockefeller University Press 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7543090/
https://ncbi.nlm.nih.gov/pubmed/33044555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006194
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